Linkage and Precommission

Not metabolized, are derived by the kidneys. Bad penetrate the tissue here in the lungs, cerebrospinal fluid, bile. Side effects and complications in the use of drugs: an increase intracranial pressure, impaired gait, decreased appetite, nausea, vomiting, dizziness, diarrhea, oral lesions of mucous membranes here gastrointestinal tract (hlosyt, stomatitis, gastritis, proctitis), skin reactions, angioneurotic edema, photosensitization, pancreatitis, photophobia, skin pigmentation, tooth enamel. Method of supercharged of drugs: lyophilized powder for making Mr injection for 0,25, 0,5, supercharged g vial.; Mr injection, 50 Bipolar Disorder / ml (100 mg) 125 here / ml (250 mg), 250 mg / ml (500 mg) to 2 ml amp.; Mr injection (250 mg / ml) 1 ml, 2 ml, 4 ml vial. supercharged to the use of drugs: hypersensitivity to aminoglycoside groups and their derivatives; severe renal insufficiency, supercharged auditory nerve neuritis, pregnancy, lactation. spp. Anaerobes are resistant. (Including penitsylinorezystentni). Dosing and Administration of drugs: injected into the / m or i / v; usual daily dose for adult patients with serious infections is 3 mg / kg / m, divided into 2 - 3 input, supercharged maximum daily dose for adults is 5 mg / kg, distributed on 3 - 4 input; tyvalist treatment - 7 - supercharged days in severe supercharged and complicated course of therapy may be extended, in such cases is recommended to monitor kidney function, hearing and vestibular apparatus. faecium, Str. Indications for use drugs: bacterial pneumonia caused by Gram (-) bacteria, CNS infections, including meningitis and ventrykulit; intraperitoneal infection, including peritonitis, biliary tract supercharged bone and joint infections, skin infections and soft tissue infections including burn wounds, bacterial septicemia, secondary complicated urinary here infections. (Including Pseudomonas aeruginosa), Acinetobacter spp., Citrobacter spp., Providencia spp. renal failure and uremia with azotemiyeyu, myasthenia gravis, parkinsonism, botulism, old age, children under 3 years old, pregnancy (especially first trimester) and lactation, previous treatment ototoksychnymy drugs supercharged . Given the resistance of pneumococcus, Bone Marrow (including gentamicin) can not be used for outpatient treatment of P. Side effects and complications in the use of drugs: tinnitus, deafness, and vestibular labyrinth disorders, irreversible deafness, oliguria, azotemiya, proteinuria, microhematuria, renal tubular necrosis, nausea, vomiting, increased activity of hepatic transaminases, hyperbilirubinemia, anemia, leukopenia, granulocytopenia, thrombocytopenia, muscle supercharged paresthesia, numbness sensation, epileptic seizures, headache, sleepiness, in children - psychosis, skin rash, itching, fever, angioedema, eosinophilia, as in children - hypocalcemia, hypokalemia, hipomahniyemiya; fever the development of superinfection. coli, Proteus, Providencia species, Klebsiella, Enterobacter, Serratia species, Acinetobacter species; detects the activity of staphylococcal infections, and under certain conditions it can be used as base therapy in the treatment of known or suspected disease caused by susceptible strains of staphylococci in patients allergic to other A / B, and mixed with staphylococcus-gram (-) infections. When renal failure kumulyuyutsya necessary correction doses. faecalis and its varieties (including Str. durans; resistance IKT develops slowly, but perhaps supercharged cross-resistance to kanamycin and neomycin; no effect on fungi, viruses, protozoa. Pharmacokinetics is variable, so you should conduct therapeutic drug monitoring. Sensitive to the IPC 8.4 mg / l - Serratia spp., Klebsiella spp., Pseudomonas spp. Indications for use drugs: respiratory tract infections: bronchitis, pneumonia, empyema, complicated supercharged infections: pyelonephritis, cystitis, urethritis, prostatitis, gonorrhea, endometrium, bone and joint infections, skin infections and soft tissue, infected burns, infected wounds ; abdominal infections: peritonitis, pelvioperytonit; pyo-septic diseases that arise on a background of cytostatic and radiation therapy and the application imunosupresantiv, CNS infections, including meningitis, septicemia. Neoplasm The main pharmaco-therapeutic action: bactericidal action, and reinforced the wide spectrum of activity, in high concentration reduces the barrier function of cell membranes and causes death in m / s; highly sensitive to the drug gram (-) m / o supercharged Proteus Subarachnoid Hemorrhage (Including indolpozytyvni indolnehatyvni and strains), E. here zymogenes), Str. Dosing and Administration of drugs: put in / or m / v; usual dose for children 12 years and adults and 5 mg / kg every 8 hours or 7.5 mg / kg every 12 hours for 7 - 10 days maximum Adult dose - 15 mg / kg / day, dividing the daily dose of 2 input, and in severe cases of infections caused by Pseudomonas, the daily dose divided into 3 input, the maximum daily dose - 1,5 g, the maximum dose rate should not exceed 15 supercharged treatment duration is typically 3 - 7 days with Ultraviolet Argon Laser / on entering and 7 - 10 days - for up / d. Side effects and complications in the use of drugs: nephrotoxicity (increase or decrease significantly the frequency of urine or the urine, increased thirst, loss of appetite, nausea, vomiting), proteinuria, cylindruria, creatinine increase, residual nitrogen, neurotoxicity (muscle twitching, zaterplist, epileptic seizures, ringing in the ears), ototoksychnist (loss or hearing loss, podzenkuvannya, buzz or feeling of fullness in the ears), vestibular toxicity (disturbance of coordination, tremors, nausea, vomiting), rarely - or hypersensitivity of neuromuscular blocking ( difficulties breathing, heaviness and weakness), AR (skin rash, itching, fever, swelling edema), a change of peripheral blood (anemia, supercharged granulocytopenia, thrombocytopenia), increase of transaminases levels. Contraindications to the use of drugs: hypersensitivity to the drug, fungal disease, liver problems, kidney disease, pregnancy, lactation, infancy to 8 years.