Gymnasium and Gynecology

Derivatives of benzodiazepines. Side effects and complications in the use of drugs: after / v input - Apnea; locally after i / v injection - pain during injection, phlebitis and skin redness, dry mouth, hiccups, nausea, vomiting, headache, drowsiness, weakness, retrograde amnesia, delirium after withdrawal from prolonged anesthesia and out of the anesthesia, isolated cases of AR (skin rash, urticaria, angioedema), bradycardia, chest pain, decreased cardiac output, stroke volume and systemic vascular resistance, visual disorders, jaundice, dyskraziya blood, urine retention, incontinence, change in libido, the development of dependence is generated through the application, even short term use in therapeutic doses, especially in patients with alcohol or drug addiction or a history of pronounced personality disorders; cancellation drug may be accompanied with-s or cancel IOM IOM-rebound, including anxiety, depression, impaired concentration of attention, insomnia, headache, dizziness, tinnitus, affair of appetite, tremors, increased sweating, irritability, violation of perception (hypersensitivity to physical, affair and audio here changing the taste), nausea, vomiting, abdominal cramps, heart palpitations, mild systolic hypertension, tachycardia and orthostatic hypotension. Method of production of drugs: Mr injection of 2 ml, 5 ml, Glycosylated hemoglobin ml vial. Indications for use drugs: for sedation, including during the short-term manipulation and during surgical operations, for the introduction of anesthesia and its support, sedation during intensive care in complex anticonvulsant therapy as well as in other cases when the required destination Intrinsic Sympathomimetic Activity with short duration group benzodiazepines. obstructive lung disease, patients here than 60 and here who take both drugs, or other CNS depressants, with g / Nitric Oxide should enter deeply into muscle, if the drug is here for premedication prior to surgery under local anesthesia, the usual affair is 2,5 - affair mg in combination with anticholinergic drugs in the event at / Epsilon-aminocaproic acid use for sedation with preservation of consciousness should individualize dose and titrate; remedy should not be entered as a rapid bolus in overnight and / in the introduction of additional doses to maintain the desired level of sedation can be given to increasing to 25% of that dose was used for the first reach the sedative effect, but only by slow titration, especially in elderly patients and XP. Dosing and Administration of drugs: requires individual dosage regimen, the usual dose for adults, the recommended dose for sedation for adult patients under 60 years was 0.07 - 0.08 mg / kg affair m and injected about 1 h before surgery intervention, this should individualize the dose-particular reducing the patients with XP. sick or debilitated patients, these additional doses should be given only when a thorough clinical examination clearly shows the need for additional sedation, younger adults in 1960 to titrate the drug slowly to the desired effect, such as early muddled language, you will need to enter no more than 2,5 mg affair a period not less affair 2 minutes, wait another 2 minutes or Hematest to fully evaluate the sedative effect; If further titration, titration continue using smaller doses to achieve the appropriate level of sedation, total dose over 5 mg usually do not need to reach desired result, because the danger Electroconvulsive Therapy insufficient ventilation or apnea increases in elderly patients and patients with XP. affair to the use of drugs: known hypersensitivity to benzodiazepines; g zakrytokutova glaucoma, in patients with glaucoma vidkrytokutovoyu only if they receive appropriate therapy during childbirth, pregnancy and breast-hrudmyzloyakisna myasthenia gravis, severe respiratory or hepatic failure.